Here comes a more precise version of CRISPR
Beam Therapeutics is the first company to go after disease with a more precise genome-editing tool, called base editing.
The technology: DNA is made up of lots of combinations of base letters. Base editing, developed by Harvard chemical biologist and Beam co-founder David Liu, is designed to target just one base out of billions within the genome.
CRISPR 2.0: The traditional CRISPR system cuts a whole gene—a sequence of different base letters. Liu’s base editors directly convert a single base from the mutated form to the corrected form.
Treating disease: Beam hasn’t said what diseases it will focus on, but the firm says base editing could be used to treat some of the most devastating genetic disorders.
The technology: DNA is made up of lots of combinations of base letters. Base editing, developed by Harvard chemical biologist and Beam co-founder David Liu, is designed to target just one base out of billions within the genome.
CRISPR 2.0: The traditional CRISPR system cuts a whole gene—a sequence of different base letters. Liu’s base editors directly convert a single base from the mutated form to the corrected form.
Treating disease: Beam hasn’t said what diseases it will focus on, but the firm says base editing could be used to treat some of the most devastating genetic disorders.
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